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2: Birth Defects, Prenatal Diagnosis, and Fetal Therapy

Chapter Objectives
Upon completion of this chapter, the reader will:
- be knowledgeable about the indications, risks, and limitations of maternal serum screening for birth defects, ultrasonography, fetal magnetic resonance imaging, and echocar-diography
- understand the techniques of amniocentesis and chorionic villus sampling and be able to determine when invasive diagnostic testing is indicated
- be familiar with alternative reproductive techniques and realize in what circumstances couples might benefit from such technologies
- become familiar with current approaches to fetal therapy
- be sensitive to the psychosocial needs of families who are at increased risk for bearing children with genetic disorders or birth defects
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