Upon completion of this chapter, the reader will:

• be able to explain errors in mitosis and meiosis, including nondisjunction, deletion, and translocation, and understand chromosomal structural abnormalities
  
  
• know the differences and similarities among autosomal recessive, autosomal dominant, and X-linked genetic disorders
  
  
• understand the concepts of genomic imprinting, anticipation, and mitochondrial inheritance
  
  
• understand the ways in which environment and heredity contribute to the development of multifactorial disorders